Famed American artist Andrew Wyeth, best known for his painting of a disabled young woman in a field, “Christina’s World,” has died at his home in Philadelphia early Friday, The Associated Press reported. He was 91.

Wyeth died in his sleep at his home in the Philadelphia suburb of Chadds Ford, according to Jim Duff, director of the Brandywine River Museum.

The popular realist painter captured the melancholy of the landscapes and people of rural Pennsylvania and Maine in his work. Considered one of America’s best loved artists, his paintings are some of the priciest in the world.

Born on 1917 in Chadd’s Ford, the youngest of five children of renowned painter and book illustrator N.C. Wyeth, Andrew was home-schooled by his parents — including in art.

“He was a man of extraordinary perception, and that perception was found in his thousands of images — many, many of them iconic,” Duff said Friday in an interview. “He highly valued the natural world, the historical objects of this world as they exist in the present and strong-willed people.”

His artistry was of fields and hillsides, wildlife, springhouses, farmhands, farm tools, and furniture. He was inducted into the French Academy of Fine Arts, and became the first living American artist to have an exhibition at the Royal Academy of Arts in London.